Lotion
Natural Estriol USP 0.15% and Progesterone USP 1.5%
Average 10 drop application contains 0.5 mg Estriol and 5 mg
Progesterone.
ClearPatch Natural Estriol and Progesterone Lotion is a
transdermal preparation containing Estriol USP 1.5mg/ml and
Progesterone USP 15 mg/ml (0.05/0.5
mg Estriol/Progesterone per average drop). Both Estriol
and Progesterone are fully
dissolved and easily absorbable.
Ingredients: Natural Progesterone USP 1.5% (450 mg/oz)
and Estriol USP 0.15% (45mg/oz), both derived from yams, in a lotion
base of propylene glycol*,
ethyl alcohol, water, oleic acid and
hydroxypropylcellulose. Contains no parabens.
Applications per container: One-ounce bottle delivers
about 90 10-drop applications (0.5 mg estriol and 5 mg progesterone per
10-drop application).
ClearPatch Lotion: the Clear Advantage
Excellent
transdermal absorption - absorbs readily from the skin surface.
Both
hormones are 100% dissolved and fully bioavailable.
Ease of
use: required dose is contained in a small amount of lotion, which can
be inconspicuously applied any time. Dose measurement is achieved
by counting drops.
Convenience:
small 1 oz. bottle easily fits in purse.
Human –
friendly ingredients.
Dr. John R. Lee and other authors* recommend using estriol in addition to progesterone
when progesterone alone is not sufficient to alleviate hot flashes,
night sweats, vaginal dryness and “foggy thinking”.
Consulting your health care professional is recommended before
using this product.
Dosage:
An appropriate dose is the minimal amount that alleviates hormonal
imbalance symptoms. To find out how much you need start with 5
drops once or twice daily. Increase the dose gradually until
symptoms subside or disappear; do not exceed 40 drops per day without
consulting your doctor. After 1 - 2 months try decreasing the
number of drops to find the correct dose for your body. Use the
smallest dose at which symptoms don’t reoccur.
ClearPatch Natural Estriol and Progesterone Lotion can be applied once
(in the morning) or twice a day (in the morning and before
retiring). In most cases it is better to use it twice a
day. If the late evening application causes undesired increase of
energy, apply the lotion no later than 4 hours before bedtime.
Dr. John R. Lee and other authors* recommend
using progesterone for:
Menopause or postmenopause:
5 - 20 drops once or twice daily for 21 days; discontinue for 7
days and repeat.
If discontinuation causes difficult to tolerate reoccurrence of
symptoms, the break can be shortened to 3 days. The break is
necessary to maintain the sensitivity of progesterone and estrogen
receptors, as well as to prevent its possible buildup in the body.
Women who do not menstruate can also use an easier to remember alternative application schedule:
use the lotion for 25 days of the calendar month and discontinue for
the rest of the month.
Pemenopause:
Start using in the middle of your cycle between the 10-th
and 12-th day depending on the cycle's length. First day of cycle
is the first day of menstruation. Use 5 - 20 drops once or twice
daily for 14 days. When irregular cycles cause earlier
menstruation, discontinue using until the middle of next cycle.
Cycles should become normalized after 2 - 3 months of usage.
Insufficient progesterone level in the body causes reduced sensitivity
of estrogen receptors. Initial progesterone supplementation
restores their sensitivity, which may cause some women to experience
certain symptoms related to estrogen dominance: water retention,
headache and enlarged breasts. It is important to remember that
these symptoms will disappear in two weeks to two months.
How and where to apply:
Invert bottle holding it vertically for proper drop delivery.
Gently massage to thin skin areas: palms, inner arms, chest, neck or
backside of the knees. It is best to alternate between
application sites. Apply to clean skin only. Do not apply
other lotions or creams to the area of ClearPatch application - they
can reduce hormone absorption.
In case a larger dose of progesterone is needed while using
Estriol/Progesterone lotion, you can add the necessary progesterone
dose by simultaneously using one of the ClearPatch Progesterone
lotions. Do not exceed a total of 20 mg progesterone daily.
For best results apply each lotion to
different area of skin.
Replacing HRT with natural estriol and progesterone:
If you are using standard hormone replacement therapy (HRT) and want to
switch to health-promoting natural estriol and progesterone, Dr. Lee* recommends complete discontinuation of synthetic
progestins if your therapy includes them, reduce estrogen dose
initially by half, then gradually taper off while using ClearPatch
Natural Estriol and Progesterone Lotion. Eventually, many women
can discontinue using estrogens other than estriol.
Contraindications:
Contraindications to estrogens use include the following:
1. Suspected or previously diagnosed estrogen-dependent neoplasia
(breast or advanced stage uterine cancer)
2. Active thrombosis or embolic disease
3. Undiagnosed uterine bleeding
4. Active liver disease or severely impaired liver function
Do not use Estriol and Progesterone Lotion when pregnant or planning to
become pregnant, if you experience estrogen dominance symptoms or while
using hormone-based birth control medications. Consult a
physician if you have any serious illness or use prescription
medication.
Health care professionals experienced in natural hormone replacement
therapy can be found at:
www.altmednetwork.net/whealth/doctors.html
* Information in
this publication is based on the
following books, which offer detailed explanation of women's hormone
balance
issues, hormone balance programs, as well as detailed descriptions of
how to
use natural hormones:
John R. Lee, M.D. What Your Doctor May Not Tell You About
Menopause: The Breakthrough Book on Natural Progesterone.
John R. Lee, M.D. What Your Doctor May Not Tell You About
Premenopause: Balance Your Hormones and Life from Thirty to Fifty.
Uzzi Reiss, M.D. Natural Hormone Balance.
Jonathan V. Wright, M.D. Natural Hormone Replacement.
Joseph McWherter, M.D. Avoiding Breast Cancer While Balancing
Your Hormones. Available online at www.femcentre.com
For external use only. Avoid contact with eyes.
Keep out of reach of children.
Store at room temperature away from strong
sources of heat and light.
Comparison
of ClearPatch® Lotions
with other brand products containing progesterone
Most creams with estriol and/or
progesterone contain micronized hormone (ground to micron-size
particles). In most of those preparations only small portion of
progesterone is dissolved, the rest is suspended as micron-size
particles. Undissolved progesterone cannot be absorbed by skin,
remains on its surface and is wasted, requiring application of larger
amounts to make up for the loss.
In making ClearPatch lotions we go one step further. We start
with micronized USP grade progesterone and estriol and make it fully
dissolved. Only in this form the hormones can be absorbed by skin
and are 100% bioavailable. The efficiency of ClearPatch lotions
allows maintaining physiological levels of progesterone using doses
smaller in comparison with creams.
Dose is easily measured and consistent: an average drop contains 0.05mg
of estriol and 0.5 mg of progesterone.
Information in this publication is not intended to replace any medical
treatment
prescribed by your physician. For those with chronic medical problems
or taking a regularly prescribed medication, please consult your health
care practitioner.
All providers of natural remedies are required to
post the following statement:
Statements in this publication have not been evaluated by the Food and
Drug Administration. The product is not intended to diagnose, treat,
cure or prevent any disease.
Information
for California residents
Gentle
Pharmacy Laboratories
11/05