Why are natural progesterone patches not available?


There are technical difficulties in making small occlusive transdermal patch to achieve delivery of necessary amounts of natural (USP) progesterone.  The amount of natural hormone is too great to be contained in a thin layer of medicated adhesive of a standard size patch - the patch would have to be uncomfortably large.  Existing occlusive progesterone patches actually do not contain natural progesterone, which is bio-identical with the human hormone.  They contain synthetic progestins, like medroxyprogesterone.  Progestins are much more potent than natural progesterone, making it possible to include smaller amount of the substance in a small occlusive transdermal patch.  However, there are substantial side effects associated with long-term use of progestins (medroxyprogesterone).

The adhesive in occlusive patch may cause an allergic reaction.  Persons with delicate skin can have another unpleasant experience: when the patch is removed after a few days, its adhesive can peel off the external layer of skin (epidermis) causing redness and oozing.

ClearPatch Progesterone USP lotion can be applied quickly and easily.  Once or twice a day application of the readily absorbing lotion makes it as inconspicuous as a patch.  The lotion is hypoallergenic, doesn't cause any skin rashes.

ClearPatch

Natural Progesterone USP contained in ClearPatch lotion does not pose any side effect risks because it is identical with the human hormone.

Gentle Pharmacy Laboratories